Start by cooking the whole grain elbow macaroni according to the package instructions. Aim for al dente texture for the best results, then drain the pasta and set aside to cool slightly.
In a large mixing bowl, add the low-fat cottage cheese, Greek yogurt, nutritional yeast, garlic powder, onion powder, smoked paprika, and a good pinch of salt and pepper. Use a blender or food processor to blend this mixture until it reaches a smooth and creamy consistency, ensuring that the flavors are well combined.
Once blended, fold in the cooked macaroni and shredded low-fat cheddar cheese into the creamy mixture. Stir thoroughly until each piece of pasta is generously coated with the cheesy sauce.
Preheat your oven to 350°F (175°C) while you prepare the baking dish.
Grease a 9x13 inch baking dish with a light coat of cooking spray or butter, then carefully pour the macaroni and cheese mixture into the dish. Spread it out evenly with a spatula for uniform cooking.
Place the baking dish in the preheated oven and bake for approximately 20 minutes. Keep an eye on it; you want the cheese to become bubbly and develop a lovely, lightly golden crust on top.
After baking, remove the dish from the oven and let it cool for a few minutes. This will help it set slightly. Just before serving, sprinkle with freshly chopped parsley to add a burst of color and freshness to your dish.